About this Research Topic
Lung diseases are amongst the leading causes of mortality world-wide and especially during the COVID-19 pandemic (caused by Covid-19 virus and subsequent strains) this has been a major concern as lungs faced the most direct damage during the progression of this disease. Lungs perform the function of providing O2 to different parts of the body and remove CO2 from the system. Among complications, patients can have pneumonia, and sepsis to more complicated diseases such as acute respiratory distress syndrome (ARDS). In pneumonia and ARDS, lung alveoli are filled with fluids which causes a shortage of air space for gaseous exchange and patients suffer from breathlessness. Patients eventually require oxygen support upon worsening of the condition. In sepsis the infection spreads, damaging different parts of the body.
These diseases and disorders existed previous to the Covid era too, but these are enhanced with additional complications post-pandemic. In light of the Covid-19 pandemic it’s of interest for the molecular biosciences community to explore these complications through omics approaches.
Different types of OMICs methodologies such as genomics, proteomics and metabolomics are increasingly being used in identification of disease markers, disease progression and management. Recently there have been multiple articles reporting various aspects of COVID-19 virus condition in patients using NMR spectroscopy, mass spectrometry, and genomics methods. Summarizing these studies as well as new findings in the field is currently relevant, and this Research Topic will contribute to our current understanding.
NMR spectroscopy and mass spectrometry have been used in the study of ARDS and Pneumonia regularly. The effected population and complexities have increased multiple times since the onset of the pandemic and still affect populations in various parts of the world. A better understanding of the abovementioned aspects will help in early diagnosis and better management of the diseases.
In this Research Topic, we welcome:
• updates on additional complications happening in lung diseases in response to Covid-19 infection.
• articles in the above area where OMICs methods (genomics, proteomics, metabolomics) have been used to study various changes leading to inflammation and fluid accumulation inside alveoli leading to breathlessness.
• research suggesting better early diagnosis, disease progression and management.
• effects of Covid-19 in lung diseases and additional complexity of the lung disorders such as pneumonia, sepsis and ARDS using omics approaches.
These diseases and disorders existed previous to the Covid era too, but these are enhanced with additional complications post-pandemic. In light of the Covid-19 pandemic it’s of interest for the molecular biosciences community to explore these complications through omics approaches.
Different types of OMICs methodologies such as genomics, proteomics and metabolomics are increasingly being used in identification of disease markers, disease progression and management. Recently there have been multiple articles reporting various aspects of COVID-19 virus condition in patients using NMR spectroscopy, mass spectrometry, and genomics methods. Summarizing these studies as well as new findings in the field is currently relevant, and this Research Topic will contribute to our current understanding.
NMR spectroscopy and mass spectrometry have been used in the study of ARDS and Pneumonia regularly. The effected population and complexities have increased multiple times since the onset of the pandemic and still affect populations in various parts of the world. A better understanding of the abovementioned aspects will help in early diagnosis and better management of the diseases.
In this Research Topic, we welcome:
• updates on additional complications happening in lung diseases in response to Covid-19 infection.
• articles in the above area where OMICs methods (genomics, proteomics, metabolomics) have been used to study various changes leading to inflammation and fluid accumulation inside alveoli leading to breathlessness.
• research suggesting better early diagnosis, disease progression and management.
• effects of Covid-19 in lung diseases and additional complexity of the lung disorders such as pneumonia, sepsis and ARDS using omics approaches.
Keywords: Critical care, Lung, Covid-19 infection, ARDS, Pneumonia, Ventilation
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